First, what is the difference between the 10.5.7 update and the 10.5.7 Combo update?

Has anyone done the update yet and has it worked?

Any issues

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ASUS P5Q3 Deluxe WIFI@N
Intel core 2 E8500
8gb Gskill dddr3 memory
EVGA 9800GT Graphics card
2 SATA II 500gb hard drives
1 Samsung SATA DVD drives
Mac OS X 10.6.1, Win Vista 64bit, Win 7 64 bit RC
Ubuntu Linux