I've been using Zephyroth's 10.5.2 rev1 on my HP Pavillion and everything ran smooth as silk. With nothing but time to waste I decided to try another release for my AMD machine and concluded that Leo4allv3 would be a good candidate. So first off some specs....

AMD Athlon 64 X2 3800+
1GB DDR2 533MHZ
200GB SATA HDD
nForce 430
ASUS A8M2N-LA
Geforce 7300 GS PCIE X16
Realtek ALC888 onboard with digital out

Install went perfect the second time around (first time I chose the wrong nForce file as my board needed the newer one.. my bad not Eddie's), and on reboot I was shocked to actually hear sound as I had to use a Linux dump and the HDA Patcher with Zephyroth. Checking my sound preferences shows not only sound, but ALL ports working and available on my sound card! About the only thing I had to fix myself with this release was my LAN. When I installed Zephyroth I discovered the onboard LAN was a no go in OS X so I purchased a cheap PCI card. After installing the tulip.kext everything is running perfect. Great release for AMD users!