iATKOS v7 has worked well for me on an Asus P5B with Intel Core 2 Duo E6400, Asus P5B Premium (Vista Edition) with Intel Core 2 Quad Q6600, MSI K9N v3 with AMD Athlon 64 X2 4200+ and an old Dell 8400 with a Pentium 4 Prescott.

Not everything has worked out of the box, of course, but booting from a DVD, installing, booting the install and getting a basic setup has worked on all of them.