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System details:

Zephyroth 10.5.1 + eddie11c update + LeoGraphics update
EFI-PC GUID
AMD Athlon 64 x2 5000+
2 GB 667Mhz DDR2 Memory
500Gb WD SATA drive
ATI 2400HD graphics
Realtek 883 Audio

My xbench score increased a whopping ~20 points when I switched to PC EFI + GUID!