I have nforce4 MB with new modified AplleNforceATA to allow more than 3 GB of ram and with the new kext I can no longer use my sata dvd drive. This is a known issue with that kext. Either way I wasn't able to burn dvd with the previous kexts either. So yes it will work no problems with your sata hdd but your dvd burner may have issues after install. Good luck !