After some time in MacOS mouse stops to move as it should be. The cursor is being moved on a very small distance with significant delay. One time this was fixed on its own but mostly I have to spawn iterm with spotlight and reboot.
Applies only to movemet, buttons/scrolling works perfectly.
Applies to al mice in system: touchpad, usb mouse, bluetooth mouse.

Any ideas?

Admin Edit: Thread renamed

Addendum by R0GUE
To summarise this for future reference; it is not a 'mouse bug' per se, but a dual core timing issue.
Symptoms include:
• Mouse lag - early signs are drag and drop inaccuracies, trail skipping
• GUI lag - Finder window movement becomes choppy and acceleration degrades
• Random restarts - caused by the 'divide by zero' error resulting in kernel panic
• -10810 error - applications will not start until a restart or log out/in
• increased CPU fan noise and temperatures - due to dual core synchronisation errors
• general erratic behaviour - system feels sluggish, unresponsive at times

Remedy (Temporary)
• Boot using the 'cpus=1' kernel flag - this can be done at the beginning of each boot at the Darwin boot prompt, or permanently by editing the com.apple.boot.plist which can be found in: /Library/Preferences/SystemConfiguration/

Addendum by Naquaada
This error must not affect all Dual-Core systems, they can work without problems. The most Photoshop users have this issue, maybe the software installes something what an AMD Dual-Core cpu doesn't like, Adobe software needs a lot of resources and makes various changes in the operating system.

Why don't you try to reload the kext for the mouse. What type of mouse is this, USB or PS/2?

as I've already said, this applies to all mice at the same time (PS/2 touchpad, USB mouse, BT mouse). I've tried to turn BT on/off (thus "restarting" BT mouse) but that didn't help.

Slow down your memory timings I guarantee it will help

can you please say, how *this* could be connected with memory timings? I'm running 333MHz clock (DDR2), no overclocking etc.

BTW, my BIOS doesn't allow memory underclocking.

What board do you have?

farcaller, i believe you have the same problem that i and numerous others are experiencing. does your mouse also jump around a bit too? that is what happens for me (and others). i've also noticed that the GUI is actually a lot more laggy too (window animation, dock animation, etc). as of yet, there is no known cause or solution to this problem. as far as i know, it is not memory timing because my memory (as well as others i've talked to) are set to stock settings. leopard may be different, but I have to say that this was never an issue for me in tiger. what's even more annoying is no one is acknowledging this as a "real" problem, which is very frustrating because it IS a "real" problem, as it means at least one reboot every day. and, as a side note, rebooting is also very frustrating for me because i suffer from the sound volume back-to-default-level-on-reboot issue that other people are also not considering a "real" problem. well, all i can say is good luck getting help with this. if you do, let me know.

specs, once more:
ASUS A8N-SLI Premium NF4
AMD 3800+
1GB DDR2 400
evga 8800GT 512mb

Just because something is on its stock setting doesn't mean changing it won't make a difference, I am telling you what works for me, I had this bug usually after about 3 hours usage, I don't have it any longer, the only difference are my memory timings.

what type of memory do you have?

At the moment kingston DDR400 but I've tried it with a couple of other sticks of ram I have lying around

Try changing cas latency to 3
Row cycle time to 18
Row Refresh time to 18 or higher

See if it makes a difference before you tell someone else that it doesn't work