Thought i'd chime in with my results. I have found it certainly a lot more stable, going at least 15hrs without issues - where previously it would only manage 3hrs tops before an app would quit. I also haven't experienced the jumpy mouse since adding the flags, but have still received the -10810 error a couple of times after prolonged uptime.

Also Rogue kindly pointed out that Firefox contains 2 cpuids, so I promptly marvinised the bastards. This seemed to have solved the random crashing of FF. I had overlooked this, I've run Marvins in the past but since Mozilla is constantly releasing updates (especially for FF3) I think the cpuids had been rewritten somewhere along the line.

Oh well, new mobo here I come, maybe an intel chip while i'm at it!

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 Mac OS X 10.6.4 Retail || Intel Core2 Duo E8200 2.66GHz || Gigabyte G31M-ES2L || GeForce 6600 GT 128MB || Realtek ALC883 Audio || Realtek RTL8169 LAN || Samsung SpinPoint F1 1TB HD || Sony Dual Layer IDE DVD RW DW-D22A || Apple Aluminium Keyboard || Mighty Mouse

 MacBook Pro || 2.4Ghz Core 2 Duo || 200Gb HD || 2Gb Ram || NVIDIA GeForce 8600M GT

 iPhone 4 || 16Gb