To summarise this for future reference; it is not a 'mouse bug' per se, but a dual core timing issue.
Symptoms include:
• Mouse lag - early signs are drag and drop inaccuracies, trail skipping
• GUI lag - Finder window movement becomes choppy and acceleration degrades
• Random restarts - caused by the 'divide by zero' error resulting in kernel panic
• -10810 error - applications will not start until a restart or log out/in
• increased CPU fan noise and temperatures - due to dual core synchronisation errors
• general erratic behaviour - system feels sluggish, unresponsive at times

Remedy (Temporary)
• Boot using the 'cpus=1' kernel flag - this can be done at the beginning of each boot at the Darwin boot prompt, or permanently by editing the com.apple.boot.plist which can be found in: /Library/Preferences/SystemConfiguration/

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MacBook Pro 15" | Mac OS X 10.6 • 2 GHz Intel Core Duo • 2 GB DDR2-667 • ATI Radeon Mobility X1600 128 MB • 100 GB Serial-ATA
Hackintosh | Mac OS X 10.5.6 • 3 GHz AMD Athlon 64 X2 6000+ • MSI K9N AM2 • 2 GB DDR2-667 • NVIDIA GeForce 8800 GT 512 MB • ALC888 Audio • 300 GB Serial-ATA
iPhone 3G • 8 GB