I've had this for a while and couldn't find any info before. I'm happy to know that it's not an exotic problem on my machine, though. ^^

I was noticing two errors I get in the console quite often:
> mDNSResponder[16]: mDNSPlatformRawTime: last_mach_absolute_time 409FDBDC0000333D
> mDNSResponder[16]: mDNSPlatformRawTime: this_mach_absolute_time 40987CA10000333D

Checking the source I gathered that somehow the timers of the cores get out of sync and in whichever core the mDNSResponder thread is executing it gets a different time. In some cases this seems to crash the gettimeofday function which probably relies on those timers. Sometimes the crash only affects applications that can easily be restarted but sometimes a system process crashes which either gets restarted (resulting in the lag - i usually notice crashrepoter hogging cpu when that happens) or result in errors like the -10810 one.

In my case it doesn't happen that often but rather regularly, about once a day. I don't think Photoshop is a trigger for it in my case. In "light" cases I notice that Firefox and Transmission are the most affected and sometimes I get "bad" cases when almost all apps begin to crash. Usually, if I just let it sit for a while the situation calms down again.

I tried to tweak my memory timings with no success.