Rev 2 didn't fix my mouse/keyboard issue, and adding in the logitech drivers didn't help either.

I'm certian that this mouse/keyboard issue isn't so much a mouse/keyboard issue but a USB support issue directly related to my motherboard. Others are having the same issues on the AMD nvidia reference-like motherboard models(Foxconn amd 590, evga amd 590, bfg tech amd 590). My only hope is to cross my fingers that another build might work for me.