My specs are:

Motherboard: ASUS M2A-VM, Socket AM2, AMD 690G Chipset, RS 690 Chipset
AMD Ahtlon 64, 3500+ CPU
2GB Ram
IDE (Slave) Sony DVD-RW DRU-180A
IDE (Master) Western Digital WD2500 HD 250GB
One 250GB partition, MBR-formatted
Radeon X1250 Graphics (Onboard)
Realtek RTL8111B Gigabit Ethernet (Onboard)

I know all this CAN work, because I had Leopard running on this machine fine before trashing it with the iPhone SDK (which I now know needs to be installed without the CHUD support).

Thanks.