Adobe CS 3 Design Premium
Adium
AppTrap
Cyberduck
BetterZip (with Rar installed)
Colloquy
DVD2oneX2
Fairmount
GrabUp
Growl
iLife 08
iWork 08
Little Snitch
Pacifist
Perian
Safari
TextMate
Toast 9
Transmission
Unison

as for the "Adobe Suite" i really didn't want to put all versions of the same software 0_o at least relativity he same

@ROUGE

If you use apptrap check hazel out it has that feature plus it can watch folders for specific rules and organize or label your files according to a pretty extensive set of rules.

mu commander ;-)

Xslimmer (slims your apps down, saving you space)
Monolingual (removes un-needed language support, giving you allot more space)
Handbrake (rips all copywrite dvd to MP4 format, many encodes)
MacTheRipper (rips all copywrite dvds. maintaining dvd format)
MacPAR deLuxe (rar files, par2)
Senuti (copy any ipod)
OnyX (system performance, maintenance)

My most used and beloved apps, nowadays :)

Photoshop
Mathematica
TextMate
Transmit

Interface Builder
XCode

butler: a nice small app laucher

it seems no one has suggested the infamous utility "AMD Software Update" by Zeph. :cool:

Quicksilver - it makes everything faster and more efficient.

Picasa
AppDelete
CheetahWatch