Move your Desktop
 

My OS X drive is only 57.27 Gigs, my Vista drive is 250 Gigs.

HOW do I set up OS X to use a folder on the NTFS drive?

I've heard I could with the assign feature...My intention is to use the same folder as Vista uses.

It is possible to move your home folder to another drive, though i wouldn't use a ntfs partition for the task as existing 3rd party ntfs drivers such as MacFuse are no way reliable or fast enough imho. Your best bet is to repartition your main windows drive and format it HFS.

Open Accounts from your System Preferences, right-click the account whose home folder you want to change, and select Advanced Options. Inside, just point the home directory to where you want it to live.