Ya, I've never had a problem, but I don't leave my any of my machines running 24-7. My son probably does - but he's using a single core Turion64 socket 754 CPU. The longest any of my dual (quad) cores run is 15-20 hours at a stretch (well, except when, ummm, using Transmission a few times when they had to be up for a couple of days while Transmission, ummm, finished... what it was doing...)

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Running both 10.5.8 and 10.6.4 on my stinking AMD/ATi machine...

the only time i reboot or shut down my computer is when i have to for an update

so my computer is always running it could be weeks before i do a restart

I just switched back to two cores, because a single core is just too slow for most applications I use.

i think it is a hit and miss for people because non of my apps crash and I hardly ever turn off photoshop it is always running in the background

Do anyone knows if this happened in tiger? I dont remember, in fact when i upgraded to dual core i changed to leopard so i dont know. I want to attempt to install tiger and update to 10.4.11 but i remember i couldnt before, Can i use the software updater? (Zephyroth's). I know there are kernels, but i dont know about updates.

@bhast2, yes, im with 1 core and its slow... meh

i've start to fiddle arround with some bios settings... maybe there are some options to solve that kind of problem!

changed:
disable: CnQ
memory CL timings raised from CL5 to CL6
Disabled some ACPI settings
Disabled Enhanced halt state
Disabled Advanced Virtual Machine
Disabled USB Legacy Mode
Disabled PCI Busmaster

leopard is working fine atm since 2 hours no crashes no mousejumps, i will report if the issue happens again!

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HomeHackintosh:
AMD Athlon64 X2 4400 :: ASRock ALiveNF5-eSATA2+ R3.0 :: Corsair 2GB DDR2-800 :: Gainward Geforce 8800GS PCI-E :: Maxtor 250GB SATA HD :: Audiotrak Maya 44 USB :: Phillips 22" 220AV TFT ::
Custom 10.5.5 Voodoo_Beta2 Kernel

Minimacbook:
Acer Aspire One A150X Netbook :: Intel Atom 1,6Ghz :: 1GB DDR2 :: Seagate 120GB SATA HD :: Acer 8,9" Crystal Bright TFT ::MSI Wind OSX 10.5.4 upgraded to 10.5.5 & Voodoo_Beta2 Kernel

after 5 hours intensive use of macOS with the settings above still no mousejumps or crashes!!!
i made some hardcore tests to run many heavy applications at the same time e.g. eyeTV, photoshop, reason, toast, adium, UT2003, firefox (about 50tabs lol) and adium(about 10chattabwindows) without any issues!
i will check it out till today evening, if the problems doesnt come back i will change the bios settings back to normal and lemme see what happens!

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HomeHackintosh:
AMD Athlon64 X2 4400 :: ASRock ALiveNF5-eSATA2+ R3.0 :: Corsair 2GB DDR2-800 :: Gainward Geforce 8800GS PCI-E :: Maxtor 250GB SATA HD :: Audiotrak Maya 44 USB :: Phillips 22" 220AV TFT ::
Custom 10.5.5 Voodoo_Beta2 Kernel

Minimacbook:
Acer Aspire One A150X Netbook :: Intel Atom 1,6Ghz :: 1GB DDR2 :: Seagate 120GB SATA HD :: Acer 8,9" Crystal Bright TFT ::MSI Wind OSX 10.5.4 upgraded to 10.5.5 & Voodoo_Beta2 Kernel

As far as this issue is concerned I'm one of the lucky ones. I have has sporadic problems with -10xxx errors and the mouse movement. My CPU is a X2 Brisbane 5000+ Black Edition (Unlocked Multi) Stock 2.6GHZ Running at 3.2GHZ with 4gb ddr2 800 @ 886. I'm running a new install of Zephs Rev2 with 10.5.4 (ASU) and modbin kernel 9.4.0. My current uptime is over 2 days not a single issue.

For what its worth i use this to stress test rather than running a bunch of apps, but using this plus a bunch of processes should stress nicely. http://www.soft32.com/Download/Free/CPUTest/4-199513-1.html . The method I use for CPU Test is 32 Instances small and 10 repetitions . YMMV .

PS

2 Days up; and running Transmission (seeding many GB) + the usual's, Firefox will Crash sometimes over night but not resulting in -10xxxx errors anymore with this install.

My computer is online for about 3 or 4 days. Transmission crashed last night, division by zero. My installation has maybe a speciality: It was installed on a single-core system, then ported on a dual-core computer. Have you guys with the stuttering problems tested Onyx? I made some additional settings in my system, maybe this will to the trick.

If it's a mouse problem (like the thread was called first), we should compare the mouse connections. What is you mouse connection and configuration? Here's mine:

Mouse: Wireless Mouse of the Logitech Cordless Internet Navigator Keyboard/Mouse combination
Connection: PS/2
Type: Optical
dpi: 800 (not sure)
Speed setting: 3 (third bar from the left)
Space needed for desktop: 2x2 cm (0,78x0,78 inch) for 1600x1200 pixel
Underground: plain table (!)

I'm actually running seren's test program, it finished over 920 tests sucessfully. EDIT: And I get every time that damn authentifcication error!

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2 Opteron systems: OSx86 10.5.8, Andy's 9.8.0 kernel, Asus A8N-SLI Premium, Opteron 185 o'clocked @ 2 x 2,95 GHz (2nd system 2.6 GHz), ATI Radeon HD2600XT 256MB Dual-Monitor 2x HP L2035, 4 GB RAM, Griffin FireWave as main audio device, Marvell + nForce LAN, Asus U3S6 USB3/SATA6 card, 5,5 TB harddisk, Firewire 800 card, Apple Remote + eHome IR receiver, 2x Wacom serial graphics tablet, Canon Pixma iP4700, Logitech Internet Navigator wireless keyboard/mouse combination.

My Audio stuff: M-Audio Transit USB (default audio), M-Audio ProFire 610, M-Audio ProFire Lightbridge (34 channels) using Creamware A16 ADAT converter • MIDI: M-Audio Midiman 4x MIDI interface • Behringer Audio Mixers: Xenyx 1002, Xenyx 1002FX, Xenyx 1202FX, Eurorack UB1002FX, Eurorack MX1804FX, Eurorack MX262A • FX devices: Lexicon MPX100 DSP, Behringer DSP-1000 Virtualizer, Behringer MiniFEX 800 DSP, Behringer Multicom Pro MDX4400 compressor • RETRO: MSSIAH midi/sequencer/synthesizer cardridge for the C64 (Dual-SID), Steinberg M.S.I. MIDI Interface for C64

nah, its not the mouse....its something with the kernel...or software based error